The New York Mets (11-6) will try to avoid losing just their second series of the season when they face the Minnesota Twins (6-12) on Wednesday afternoon. New York notched a 5-1 win over Minnesota in Monday’s opener, but the Twins bounced back with a 6-3 win on Tuesday. Minnesota has an opportunity to win consecutive games for the first time in two weeks. The Twins are in fourth place in the American League Central, while the Mets are in first place in the National League East.
First pitch from Target Field in Minneapolis is set for 1:10 p.m. ET. Minnesota is a -117 favorite on the money line (risk $117 to win $100) in the latest Twins vs. Mets odds from DraftKings, while the total number of runs Vegas thinks will be scored, or the over/under, is 8.5. Before making any Mets vs. Twins picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 4 of the 2025 MLB season on an 8-3 run on MLB money-line betting picks (+340). Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Twins vs. Mets and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Mets vs. Twins:
- Twins vs. Mets money line: Minnesota -125, New York +105
- Twins vs. Mets over/under: 8.5 runs
- Twins vs. Mets run line: Minnesota -1.5 (+166)
- MIN: The Twins have gone Under in seven of their last eight games
- NYM: The Mets have gone Under in eight of their last 10 games
- Twins vs. Mets picks: See picks at SportsLine
- Twins vs. Mets streaming: FuboTV (Try for free)
Why the Twins can cover
Right-handed pitcher David Festa is getting another start for Minnesota after being called up from Triple-A St. Paul last week. Festa allowed one unearned run across 4.2 innings with four strikeouts against Detroit on Friday, earning another opportunity in this game. Minnesota has won two of its last three games, including Tuesday’s victory over New York.
Ryan Jeffers and Harrison Bader had three hits apiece in that game, while Byron Buxton added two singles and two runs. The Twins finished with a season-high 13 hits, generating some much-needed momentum heading into the series finale. First baseman Ty France leads the team with 17 hits and a .288 batting average in 59 at-bats. See which team to back at SportsLine.
Why the Mets can cover
New York is coming off a loss on Tuesday, but it has still won nine of its last 12 games. The Mets have not lost a series since their opening series, when they lost two out of three against Houston. They are sitting atop the NL East standings and have allowed the second-fewest runs in the majors.
First baseman Pete Alonso hit a home run on Tuesday, giving him five homers and a .356 batting average this season. Right fielder Juan Soto also left the yard in the second game of the series, giving him back-to-back games with a homer. The Mets have significantly more firepower in their lineup, and they are facing an inexperienced starter in this game. See which team to back at SportsLine.
How to make Mets vs. Twins picks
SportsLine’s model is leaning Over on the total, projecting 10.3 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks.
So who wins Twins vs. Mets, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.